{"id":7677,"date":"2025-08-14T14:29:23","date_gmt":"2025-08-14T12:29:23","guid":{"rendered":"https:\/\/strokeneurorehab.com\/?p=7677"},"modified":"2025-08-14T14:31:52","modified_gmt":"2025-08-14T12:31:52","slug":"a-stressz-biologiaja","status":"publish","type":"post","link":"https:\/\/strokeneurorehab.com\/en\/a-stressz-biologiaja\/","title":{"rendered":"A stressz biol\u00f3gi\u00e1ja \u2013 Hogyan \u201e\u00e9geti ki\u201d az agyi ereket a kr\u00f3nikus fesz\u00fclts\u00e9g?"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\" id=\"h-1-a-tartos-stressz-testunk-szamara-vegyes-uzemmod\">1. A tart\u00f3s stressz test\u00fcnk sz\u00e1m\u00e1ra \u201evegyes \u00fczemm\u00f3d\u201d<\/h3>\n\n\n\n<p>A kr\u00f3nikus stressz \u00e1lland\u00f3 k\u00e9szenl\u00e9ti \u00e1llapotot okoz a szervezetben: aktiv\u00e1l\u00f3dik a HPA\u2011tengely \u00e9s a szimpatikus idegrendszer, ami tart\u00f3san emeli a v\u00e9rnyom\u00e1st \u00e9s a sz\u00edvdobog\u00e1st \u2013 mindez \u00e9rrendszeri terhel\u00e9st jelent. Epidemiol\u00f3giai adatok szerint m\u00e1r egy nagyobb stresszor 17\u202f%-kal, kett\u0151 vagy t\u00f6bb ilyen esem\u00e9ny pedig ak\u00e1r 31\u202f%-kal is megemelheti az els\u0151 stroke kock\u00e1zat\u00e1t. [1]<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-2-kortizol-a-tulelokeszultseg-ara\">2. Kortizol \u2013 a t\u00fal\u00e9l\u0151k\u00e9sz\u00fclts\u00e9g \u00e1ra<\/h3>\n\n\n\n<p>A stresszv\u00e1lasz sor\u00e1n felszabadul\u00f3 kortizol hossz\u00fa t\u00e1von k\u00e1ros\u00edtja az \u00e9rfalakat. Eg\u00e9rk\u00eds\u00e9rletekben a kr\u00f3nikusan magas kortizolszint cs\u00f6kkentette az endoteli\u00e1lis nitrog\u00e9n-oxid termel\u00e9st, fokozta a szuperoxid-k\u00e9pz\u0151d\u00e9st, rontotta az \u00e9relernyed\u00e9st, \u00e9s nagyobb agyi infarktusokat eredm\u00e9nyezett \u2013 mindez reverzibilis volt gl\u00fckokortikoid-receptor-antagonist\u00e1val kezelt \u00e1llatokban. [2]<\/p>\n\n\n\n<p>Teh\u00e1t a tart\u00f3s stressz miatt termel\u0151d\u0151 kortizol k\u00e1ros\u00edtja az ereket: rontja azok t\u00e1gul\u00f3k\u00e9pess\u00e9g\u00e9t, el\u0151seg\u00edti a gyullad\u00e1st \u00e9s fokozza a stroke kock\u00e1zat\u00e1t, \u00e1m ez a folyamat bizonyos kezel\u00e9sekkel visszaford\u00edthat\u00f3 lehet.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-3-endotelium-rombolasa-es-gyulladas\">3. Endot\u00e9lium rombol\u00e1sa \u00e9s gyullad\u00e1s<\/h3>\n\n\n\n<p>A stressz szerepe az endothelial dysfunctio kialakul\u00e1s\u00e1ban jelent\u0151s: az \u00e9rbelh\u00e1rtya m\u0171k\u00f6d\u00e9se romlik, ami \u00e9rsz\u0171k\u00fclethez, v\u00e9rnyom\u00e1s-emelked\u00e9shez \u00e9s fokozott tromb\u00f3zisk\u00e9szs\u00e9ghez vezet. Ugyanakkor a stressz el\u0151seg\u00edti gyullad\u00e1sos citokinek (pl. IL-6, TNF\u2011\u03b1) felszaporod\u00e1s\u00e1t, amelyek az \u00e9rfalak gyullad\u00e1s\u00e1n kereszt\u00fcl el\u0151seg\u00edthetik az \u00e9relmeszesed\u00e9st \u00e9s az atherotrombotikus stroke kialakul\u00e1s\u00e1t. [3][4]<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-4-stroke-kockazata-kulonosen-noknel\">4. Stroke kock\u00e1zata, k\u00fcl\u00f6n\u00f6sen n\u0151kn\u00e9l<\/h3>\n\n\n\n<p>Fiatalabb n\u0151k k\u00f6r\u00e9ben egy Neurology-ban publik\u00e1lt vizsg\u00e1lat szerint a k\u00f6zepes stressz 78\u202f%-kal n\u00f6velte az iszk\u00e9mi\u00e1s stroke rizik\u00f3j\u00e1t \u2013 magas stressz eset\u00e9n is n\u0151tt a rizik\u00f3, b\u00e1r m\u00e9rs\u00e9kelten. A f\u00e9rfiakn\u00e1l nem mutattak \u00f6sszef\u00fcgg\u00e9st. [5]<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-5-agy-mikro-keringes-es-neurovaszkularis-serulesek\">5. Agy (mikro)kering\u00e9s \u00e9s neurovaszkul\u00e1ris s\u00e9r\u00fcl\u00e9sek<\/h3>\n\n\n\n<p>A tart\u00f3s stressz rontja az agyi autoregul\u00e1ci\u00f3t \u2013 azaz az agyi erek kev\u00e9sb\u00e9 alkalmazkodnak a v\u00e9rnyom\u00e1sv\u00e1ltoz\u00e1sokhoz. Ennek k\u00f6vetkezt\u00e9ben kritikus agyter\u00fcletek (pl. prefront\u00e1lis k\u00e9reg, hippocampus) v\u00e9rell\u00e1t\u00e1sa cs\u00f6kkenhet, \u00e9s MRI-vizsg\u00e1latok feh\u00e9r\u00e1llom\u00e1ny-s\u00e9r\u00fcl\u00e9seket, mikrov\u00e9rz\u00e9seket is kimutattak stresszben \u00e9l\u0151kn\u00e9l. [6]<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-6-mit-tehetunk-stresszkezeles-mint-agyi-vedelem\">6. Mit tehet\u00fcnk? \u2013 Stresszkezel\u00e9s mint agyi v\u00e9delem<\/h3>\n\n\n\n<p>Stressz menedzsel\u00e9se egyszerre ment\u00e1lis \u00e9s \u00e9rrendszeri fegyver is. A mozg\u00e1s cs\u00f6kkenti a kortizolt \u00e9s jav\u00edtja az endothelium m\u0171k\u00f6d\u00e9s\u00e9t. A relax\u00e1ci\u00f3, medit\u00e1ci\u00f3, megfelel\u0151 alv\u00e1s \u00e9s t\u00e1rsas t\u00e1mogat\u00e1s fokozz\u00e1k a nyugalmi (paraszimpatikus) t\u00f3nust, ellens\u00falyozva a stressz k\u00e1ros hat\u00e1sait. [7]<\/p>\n\n\n\n<p>Ha t\u00f6bbet szeretn\u00e9l megtudni a stroke-kal kapcsolatban, akkor csatlakozz facebook csoportunkhoz: <a href=\"https:\/\/www.facebook.com\/strokeneurorehab\">https:\/\/www.facebook.com\/strokeneurorehab<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-forrasok\">Forr\u00e1sok<\/h3>\n\n\n\n<p><strong>[1] <\/strong><a href=\"https:\/\/studies.science37.com\/the-role-of-stress-in-stroke-risk-how-clinical-trials-offer-new-hope\/?utm_source=strokeneurorehab.com\">https:\/\/studies.science37.com\/the-role-of-stress-in-stroke-risk-how-clinical-trials-offer-new-hope\/?utm_source=strokeneurorehab.com<\/a><\/p>\n\n\n\n<p><strong>[2] <\/strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21921276\/?utm_source=strokeneurorehab.com\">https:\/\/pubmed.ncbi.nlm.nih.gov\/21921276\/?utm_source=strokeneurorehab.com<\/a><\/p>\n\n\n\n<p><strong>[3] <\/strong><a href=\"https:\/\/en.wikipedia.org\/wiki\/Endothelial_dysfunction?utm_source=strokeneurorehab.com\">https:\/\/en.wikipedia.org\/wiki\/Endothelial_dysfunction?utm_source=strokeneurorehab.com<\/a><\/p>\n\n\n\n<p><strong>[4] <\/strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0889159123001630?utm_source=strokeneurorehab.com\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0889159123001630?utm_source=strokeneurorehab.com<\/a><\/p>\n\n\n\n<p><strong>[5] <\/strong><a href=\"https:\/\/www.health.com\/women-stress-higher-stroke-risk-study-11690777?utm_source=strokeneurorehab.com\">https:\/\/www.health.com\/women-stress-higher-stroke-risk-study-11690777?utm_source=strokeneurorehab.com<\/a><\/p>\n\n\n\n<p><strong>[6] <\/strong><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6126243\/?utm_source=strokeneurorehab.com\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6126243\/?utm_source=strokeneurorehab.com<\/a><\/p>\n\n\n\n<p><strong>[7] <\/strong><a href=\"https:\/\/www.verywellmind.com\/prolonged-stress-symptoms-causes-impact-and-coping-5092113?utm_source=strokeneurorehab.com\">https:\/\/www.verywellmind.com\/prolonged-stress-symptoms-causes-impact-and-coping-5092113?utm_source=strokeneurorehab.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1. A tart\u00f3s stressz test\u00fcnk sz\u00e1m\u00e1ra \u201evegyes \u00fczemm\u00f3d\u201d A kr\u00f3nikus stressz \u00e1lland\u00f3 k\u00e9szenl\u00e9ti \u00e1llapotot okoz a szervezetben: aktiv\u00e1l\u00f3dik a HPA\u2011tengely [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":7678,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7677","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.1 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>A stressz biol\u00f3gi\u00e1ja \u2013 Hogyan \u201e\u00e9geti ki\u201d az agyi ereket a kr\u00f3nikus fesz\u00fclts\u00e9g? - Stroke Neuro Rehab<\/title>\n<meta name=\"description\" content=\"A kr\u00f3nikus stressz \u00e1lland\u00f3 k\u00e9szenl\u00e9ti \u00e1llapotot okoz a szervezetben: aktiv\u00e1l\u00f3dik a HPA\u2011tengely \u00e9s a szimpatikus idegrendszer, ami tart\u00f3san emeli a v\u00e9rnyom\u00e1st \u00e9s a sz\u00edvdobog\u00e1st \u2013 mindez \u00e9rrendszeri terhel\u00e9st jelent.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/strokeneurorehab.com\/en\/a-stressz-biologiaja\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A stressz biol\u00f3gi\u00e1ja \u2013 Hogyan \u201e\u00e9geti ki\u201d az agyi ereket a kr\u00f3nikus fesz\u00fclts\u00e9g? - Stroke Neuro Rehab\" \/>\n<meta property=\"og:description\" content=\"Fedezd fel a Stroke Neuro Rehab blogj\u00e1t! 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